Greg Simon, MD, MPH, is a psychiatrist and senior investigator well-known for his extensive research on practical approaches to improving mental health care. He seeks to develop and evaluate effective real-world strategies that support better mental health and wellness. Current areas of emphasis include identifying and assessing suicide risk, improving care for treatment-resistant depression, and early intervention for mental health conditions in children and youth.
Dr. Simon leads the Mental Health Research Network (MHRN), a consortium of research centers affiliated with 13 large health systems across the United States, including Kaiser Permanente Washington. This network, funded through a cooperative agreement with the National Institute of Mental Health, aims to improve the efficiency, relevance, and impact of mental health clinical and health services research. Now in its second five-year funding cycle, the MHRN is exploring a broad range of issues—including suicide prevention, improving heart health in people with serious mental illness, using electronic medical records to improve follow-up care for depression, and understanding the causes of racial and ethnic disparities in mental health care.
Dr. Simon and his MHRN colleagues are conducting several large studies across MHRN health systems, including:
Dr. Simon is an editor for the Cochrane Collaboration’s depression and anxiety review group, sits on the editorial board for General Hospital Psychiatry, and serves on the advisory board for the National Institutes of Health’s All of Us Program (formerly Precision Medicine Initiative). Earlier, he served on the editorial boards of Psychiatric Services and Psychological Medicine and chaired the scientific advisory board for the Depression and Bipolar Support Alliance. Dr. Simon has practiced adult psychiatry in Kaiser Permanente Washington's Mental Health and Wellness Service since 1990 and is a research professor in psychiatry and behavioral sciences at the University of Washington.
Depression; bipolar disorder; suicide prevention; self-management; treatment adherence
Comorbidity of mental health conditions with obesity, diabetes, heart disease, and substance use disorders.
Lin EH, Simon GE, Katon WJ, Russo JE, Von Korff M, Bush TM, Ludman EJ, Walker EA. Can enhanced acute-phase treatment of depression improve long-term outcomes? A report of randomized trials in primary care. Am J Psychiatry. 1999;156(4):643-5. PubMed
Simon GE, Goldberg D, Tiemens BG, Ustun TB. Outcomes of recognized and unrecognized depression in an international primary care study. Gen Hosp Psychiatry. 1999;21(2):97-105. PubMed
Schulberg HC, Katon WJ, Simon GE, Rush AJ. Best clinical practice: guidelines for managing major depression in primary medical care. J Clin Psychiatry. 1999;60 Suppl 7():19-26; discussion 27-8. PubMed
Simon GE, Gureje O. Stability of somatization disorder and somatization symptoms among primary care patients. Arch Gen Psychiatry. 1999;56(1):90-5. PubMed
Von Korff M, Katon W, Unutzer J, Simon G, Bush T, Lin E, Walker E, Ludman E. Principles of population-based care of patients with bipolar disorder. Bipolar Disorders. 1999;1(Suppl):19.
Revicki DA, Simon GE, Chan K, Katon W, Heiligenstein J. Depression, health-related quality of life, and medical cost outcomes of receiving recommended levels of antidepressant treatment. J Fam Pract. 1998;47(6):446-52. PubMed
Schulberg HC, Katon W, Simon GE, Rush AJ. Treating major depression in primary care: an update of the Agency for Health Care Policy and Research Practice Guidelines. Arch Gen Psychiatry. 1998;55(12):1121-7. PubMed
Goldberg D, Privett M, Ustun B, Simon G, Linden M. The effects of detection and treatment on the outcome of major depression. Br J Gen Pract. 1998;48(437):1840-4. PubMed
Saunders K, Simon G, Bush T, Grothaus L. Assessing the feasibility of using computerized pharmacy refill data to monitor antidepressant treatment on a population basis: a comparison of automated and self-report data. J Clin Epidemiol. 1998;51(10):883-90. PubMed
Lin EH, Katon WJ, VonKorff M, Russo JE, Simon GE, Bush TM, Rutter CM, Walker EA, Ludman E. Relapse of depression in primary care. Rate and clinical predictors. Arch Fam Med. 1998;7(5):443-9. PubMed
Safety planning and risk screening improved outcomes for adult patients.
A new grant funds modeling work to make personalized treatment possible.
KPWHRI research finds ways to increase use of a firearm safety tool.
Study finds that many patients who might benefit from clozapine don’t receive it.
KPWHRI researchers are contributing to better mental health care for people nationwide.