Weiwei Zhu, MS, joined Kaiser Permanente Washington Health Research Institute's Biostatistics Unit in 2009. She works closely with Affiliate Investigator Diana Miglioretti, PhD, to design studies, manage data, and conduct statistical analyses for the Breast Cancer Surveillance Consortium (BCSC) — the National Cancer Institute’s 7-site network of mammography researchers. She has been a key member of the BCSC Statistical Coordinating Center for over 10 years. Her work studying breast screening benefits and risks played an essential role in an American Cancer Society screening guideline change in 2015.
Weiwei’s current other studies include testing the effects of sitting reduction on cardiometabolic health outcomes through a large randomized trial in older adults, studying a sedentary behavior reduction and physical activity promotion intervention for the older Latino/Hispanic community, and examining the association of the 24-hour activity cycle with cognition and physical function in older adults with Senior Investigator Dori Rosenberg, PhD, MPH. Weiwei has also collaborated on research to quantify the serious risks of misuse, abuse, and addiction associated with long-term opioid use. This multi-site study used electronic health record data and survey interviews to provide estimates of long-term opioid use risks in 2 cohorts.
After beginning her medical research career as an intern at the University of Texas MD Anderson Cancer Center in 2007, Weiwei served as a biostatistician at the Moffitt Cancer Center and Research Institute in Florida.
Correlated data analysis; longitudinal data; survival analysis
Opioid misuse, abuse, and addiction
Biostatistics; breast cancer screening and surveillance
Hubbard RA, Zhu W, Onega TL, Fishman P, Henderson LM, Tosteson AN, Buist DS. Effects of digital mammography uptake on downstream breast-related care among older women. Med Care. 2012;50(12):1053-9. PubMed
Shan L, Chen YA, Davis L, Han G, Zhu W, Molina AD, Arango H, LaPolla JP, Hoffman MS, Sellers T, Kirby T, Nicosia SV, Sutphen R. Measurement of phospholipids improve diagnostic accuracy in ovarian cancer. PLoS One. 2012;7(10):e46846. doi: 10.1371/journal.pone.0046846. Epub 2012 Oct 17. PubMed
Yasmeen S, Hubbard R, Romano PS, Zhu W, Geller BM, Onega T, Yankaskas B, Miglioretti DL, Kerlikowske K. Risk of advanced-stage breast cancer among older women with comorbidities. Cancer Epidemiol Biomarkers Prev. 2012 Sep;21(9):1510-9. Epub 2012 Jun 28. PubMed
Cook AJ, Elmore JG, Zhu W, Jackson SL, Carney PA, Flowers C, Onega T, Geller B, Rosenberg RD, Miglioretti DL. Mammographic interpretation: radiologists' ability to accurately estimate their performance and compare it with that of their peers. AJR Am J Roentgenol. 2012 Sep;199(3):695-702. PubMed
Henderson LM, Hubbard RA, Onega TL, Zhu W, Buist DS, Fishman P, Tosteson AN. Assessing health care use and cost consequences of a new screening modality: the case of digital mammography. Med Care. 2012 Dec;50(12):1045-52. PubMed
New research spotlights overdiagnosis, MRI before surgery, and a new way of predicting breast cancer risk
Findings in JAMA Network Open could help guide decision-making about breast cancer screening for women 75 and older.
A study among KP members with sleep problems and osteoarthritis shows promise for overcoming obstacles to treatment.