Weiwei Zhu, MS, joined Kaiser Permanente Washington Health Research Institute's Biostatistics Unit in 2009. She works closely with Affiliate Investigator Diana Miglioretti, PhD, to design studies, manage data, and conduct statistical analyses for the Breast Cancer Surveillance Consortium (BCSC) — the National Cancer Institute’s 7-site network of mammography researchers. She has been a key member of the BCSC Statistical Coordinating Center for over 10 years. Her work studying breast screening benefits and risks played an essential role in an American Cancer Society screening guideline change in 2015.
Weiwei’s current other studies include testing the effects of sitting reduction on cardiometabolic health outcomes through a large randomized trial in older adults, studying a sedentary behavior reduction and physical activity promotion intervention for the older Latino/Hispanic community, and examining the association of the 24-hour activity cycle with cognition and physical function in older adults with Senior Investigator Dori Rosenberg, PhD, MPH. Weiwei has also collaborated on research to quantify the serious risks of misuse, abuse, and addiction associated with long-term opioid use. This multi-site study used electronic health record data and survey interviews to provide estimates of long-term opioid use risks in 2 cohorts.
After beginning her medical research career as an intern at the University of Texas MD Anderson Cancer Center in 2007, Weiwei served as a biostatistician at the Moffitt Cancer Center and Research Institute in Florida.
Correlated data analysis; longitudinal data; survival analysis
Opioid misuse, abuse, and addiction
Biostatistics; breast cancer screening and surveillance
Wang W, Lau R, Yu D, Zhu W, Korman A, Weber J. PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4+ CD25(Hi) regulatory T cells. Int Immunol. 2009 Sep;21(9):1065-77. Epub 2009 Aug 3. PubMed
Tanvetyanon T, Qin D, Padhya T, McCaffrey J, Zhu W, Boulware D, DeConti R, Trotti A. Outcomes of postoperative concurrent chemoradiotherapy for locally advanced major salivary gland carcinoma. Arch Otolaryngol Head Neck Surg. 2009 Jul;135(7):687-92. PubMed
Möller MG, Pappas-Politis E, Zager JS, Santiago LA, Yu D, Prakash A, Kinal A, Clark GS, Zhu W, Puleo CA, Glass LF, Messina JL, Sondak VK, Cruse CW. Surgical management of melanoma-in-situ using a staged marginal and central excision technique. Ann Surg Oncol. 2009 Jun;16(6):1526-36. Epub 2008 Dec 3. PubMed
Tanvetyanon T, Padhya T, McCaffrey J, Zhu W, Boulware D, Deconti R, Trotti A. Prognostic factors for survival after salvage reirradiation of head and neck cancer. J Clin Oncol. 2009 Apr 20;27(12):1983-91. Epub 2009 Mar 16. PubMed
New research spotlights overdiagnosis, MRI before surgery, and a new way of predicting breast cancer risk
Findings in JAMA Network Open could help guide decision-making about breast cancer screening for women 75 and older.
A study among KP members with sleep problems and osteoarthritis shows promise for overcoming obstacles to treatment.