Research is often lauded for finding life-saving treatments for diseases like cancer or diabetes. But consider the impact of preventing such illnesses from developing in the first place. It’s hard to describe the value of stopping illness or injury from happening. Yet that’s the goal of research on preventive care.
Most Kaiser Permanente Washington scientists study prevention, whether their work focuses on promoting health by influencing individual behavior, building sound prevention services into everyday clinical care, designing smart health coverage, or all three. By conducting their research at Kaiser Permanente Washington—which combines care and coverage—our researchers have access to data from a large, stable population over time, allowing them to discover which approaches to prevention work best.
Examples include research in areas such as:
A team of researchers at Kaiser Permanente Washington Health Research Institute (KPWHRI) produces reviews of scientific evidence that policymakers at the Centers for Medicare & Medicaid Services and the U.S. Preventive Services Task Force and others use in health care decision-making. We do this work as part of the Kaiser Permanente Research Affiliates Evidence-based Practice Center, one of 13 centers nationwide that are sponsored by the federal Agency for Healthcare Research and Quality.
We’re improving the safety and effectiveness of vaccines through clinical trials, and we’re monitoring how well each year’s new flu vaccines are working. In addition, we’re studying ways to better inform parents about the benefits and potential harms of childhood vaccines, to improve their uptake.
We’re working on several fronts to help ensure the safety of prescription drugs and other medical treatments. For example, we play a leading role in the Food and Drug Administration’s Sentinel program to monitor the safety of medical products through routinely collected electronic health care data. We’re exploring ways to improve the safety of prescribing opioid pain medications. And we often study the safety of drugs commonly used to prevent chronic conditions like heart disease, cancer, and depression.
Prevention also includes screening to detect disease before symptoms appear, to identify and treat disease at an earlier stage. Our research is improving the effectiveness of cancer screening programs so people get the appropriate tests when needed based on their particular risks. Our research is also aimed at improving clinical screening for behavioral risks such as smoking, suicidal thoughts, alcohol use disorders, and poor eating and exercise habits.
Our research in areas such as smoking cessation, healthy diet, and chronic illness care finds new ways to encourage individuals to adopt and maintain healthier lifestyles. At the same time, we’re exploring ways to reach large populations through the use of phone-based programs, websites, and mobile technologies.
Sheppard JP, Tucker KL, Davison WJ, Stevens R, Aekplakorn W, Bosworth HB, Bove A, Earle K, Godwin M, Green BB, Hebert P, Heneghan C, Hill N, Hobbs FDR, Kantola I, Kerry SM, Leiva A, Magid DJ, Mant J, Margolis KL, McKinstry B, McLaughlin MA, McNamara K, Omboni S, Ogedegbe O, Parati G, Varis J, Verberk WJ, Wakefield BJ, McManus RJ. Self-monitoring of blood pressure in patients with hypertension related multi-morbidity: systematic review and individual patient data meta-analysis. Am J Hypertens. 2019 Nov 15. pii: hpz182. doi: 10.1093/ajh/hpz182. [Epub ahead of print].
Bradley KA, Caldeiro RM, Hallgren KA, Kivlahan DR. Making measurement-based care for addictions a reality in primary care. Addiction. 2019 Apr 29. doi: 10.1111/add.14605. [Epub ahead of print]. PubMed
Lynch BM, Nguyen NH, Moore MM, Reeves MM, Rosenberg DE, Boyle T, Vallance JK, Milton S, Friedenreich CM, English DR. A randomized controlled trial of a wearable technology-based intervention for increasing moderate to vigorous physical activity and reducing sedentary behavior in breast cancer survivors: the ACTIVATE Trial. Cancer. 2019 Apr 23. doi: 10.1002/cncr.32143. [Epub ahead of print]. PubMed
US Preventive Services Task Force, Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW Jr, Grossman DC, Kemper AR, Kubik M, Landefeld CS, Mangione CM, Silverstein M, Simon MA, Tseng CW, Wong JB. Interventions to prevent perinatal depression: US Preventive Services Task Force recommendation statement. JAMA. 2019;321(6):580-587. doi: 10.1001/jama.2019.0007. PubMed
Lewis CC, Lyon AR, McBain SA, Landes SJ. Testing and exploring the limits of traditional notions of fidelity and adaptation in implementation of preventive interventions. J Prim Prev. 2019 Feb;40(1):137-141. doi: 10.1007/s10935-019-00539-2. PubMed
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
Katharine A. Bradley, MD, MPHSenior Investigator |
Jessica Chubak, PhDSenior Investigator |
Dori E. Rosenberg, PhD, MPHSenior Investigator |
Karen Wernli, PhDSenior Investigator |
Erin J. Bowles, MPHDirector, Collaborative Science |
Melissa L. Anderson, MSPrincipal Collaborative Biostatistician |
Paula R. Blasi, MPHCollaborative Scientist |
Joseph E. Glass, PhD, MSWAssociate Investigator |
Julie E. Richards, PhD, MPHAssistant Investigator |
Yu-Ru Su, PhDAssociate Biostatistics Investigator |
Annie Hoopes, MD, MPHActing Assistant Investigator |
Pamela A. Shaw, PhD, MSSenior Biostatistics Investigator |
Claire Allen, MPHManager, Collaborative Science |
Nicole M. Gatto, PhD, MPHPrincipal Collaborative Scientist |
Kelsey Stefanik-Guizlo, MPHCollaborative Scientist |
Theresa E. Matson, PhD, MPHCollaborative Scientist |
Meagan C. Brown, PhD, MPHAssistant Investigator |
Nora Henrikson, PhD, MPHAssociate Investigator |