Vaccines save lives by protecting people against infectious diseases — polio, influenza, and pneumonia to name a few. Kaiser Permanente Washington Health Research Institute (KPWHRI) is working to protect communities through research to continually improve the safety and effectiveness of vaccines for infectious diseases of public health importance.
Central to this work is testing new vaccines against emerging diseases — such as COVID-19. In March 2020, KPWHRI gave the world’s first-ever injection of an investigational vaccine for COVID-19 in a phase 1 clinical trial led by Senior Investigator Lisa A. Jackson, MD, MPH. We continue to be at the forefront of efforts to understand and combat COVID-19. To learn more, see COVID-19 research at KPWHRI.
Successes over 3 decades of KPWHRI vaccine research include:
Our current research projects on vaccines and infectious diseases include:
Li R, Weintraub E, McNeil MM, Kulldorff M, Lewis EM, Nelson J, Xu S, Qian L, Klein NP, Destefano F. Meningococcal conjugate vaccine safety surveillance in the Vaccine Safety Datalink using a tree-temporal scan data mining method. Pharmacoepidemiol Drug Saf. 2018 Feb 15. doi: 10.1002/pds.4397. [Epub ahead of print]. PubMed
Kharbanda EO, Vazquez-Benitez G, Lipkind HS, Sheth SS, Zhu J, Naleway AL, Klein NP, Hechter R, Daley MF, Donahue JG, Jackson ML. Risk of spontaneous abortion after inadvertent human papillomavirus vaccination in pregnancy. Obstet Gynecol. 2018 Jun 6. doi: 10.1097/AOG.0000000000002694. [Epub ahead of print]. PubMed
Weinmann S, Naleway AL, Koppolu P, Baxter R, Belongia EA, Hambidge SJ, Irving SA, Jackson ML, Klein NP, Lewin B, Liles E, Marin M, Smith N, Weintraub E, Chun C. Incidence of herpes zoster among children: 2003-2014. Pediatrics. 2019 Jun 10. pii: e20182917. doi: 10.1542/peds.2018-2917. [Epub ahead of print]. PubMed
Pingray V, Belizan M, Matthews S, Zaraa S, Berrueta M, Noguchi LM, Xiong X, Gurtman A, Absalon J, Nelson JC, Panagiotakopoulos L, Sevene E, Munoz FM, Althabe F, Mwamwitwa KW, Cairoli FR, Anderson SA, McClure EM, Guillard C, Nakimuli A, Stergachis A, Buekens P. Using maternal and neonatal data collection systems for coronavirus disease 2019 (COVID-19) vaccine active safety surveillance in low- and middle-income countries: an international modified Delphi study. Gates Open Res. 2021; 5:99 (https://doi.org/10.12688/gatesopenres.13305.1).
Tartof SY, Xie F, Yadav R, Wernli KJ, Martin ET, Belongia EA, Gaglani M, Zimmerman RK, Talbot HK, Thornburg N, Flannery B, Chung JR; US Flu VE Network Investigators. Prior SARS-CoV-2 infection and COVID-19 vaccine effectiveness against outpatient illness during widespread circulation of SARS-CoV-2 Omicron variant, US Flu VE network. medRxiv. 2023 Jan 11;2023.01.10.23284397. doi: 10.1101/2023.01.10.23284397. Preprint. PubMed
Lisa A. Jackson, MD, MPHSenior Investigator |
Jennifer C. Nelson, PhDDirector, Biostatistics; Senior Investigator |
Andrea J. Cook, PhDSenior Biostatistics Investigator |
Sascha Dublin, MD, PhDSenior Investigator |
Onchee Yu, MSPrincipal Collaborative Biostatistician |
Robert D. Wellman, MSPrincipal Collaborative Biostatistician |
Clarissa Hsu, PhDAssociate Investigator |
Brian D. Williamson, PhDAssistant Biostatistics Investigator |
Noorie Hyun, PhDAssociate Biostatistics Investigator |
Pamela A. Shaw, PhD, MSSenior Biostatistics Investigator |
Annie Piccorelli, PhDSenior Collaborative Biostatistician |
Doug Opel, MD, MPH
University of Washington (UW) Department of Bioethics and Humanities; UW Department of Pediatrics; UW Medical Center
John Dunn, MD, MPH
Kaiser Foundation Health Plan of Washington
Elizabeth Lin, MD, MPH
Kaiser Foundation Health Plan of Washington Family Practice;
Kaiser Permanente Washington Health Research Institute