Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
O'Leary K, Tanghe D, Pratt W, Ralston J. Collaborative health reminders and notifications: insights from prototypes. AMIA Annu Symp Proc. 2018 Dec 5;2018:837-846. eCollection 2018. PubMed
Liu Y, Wan Z, Xia W, Kantarcioglu M, Vorobeychik Y, Clayton EW, Kho A, Carrell D, Malin BA. Detecting the presence of an individual in phenotypic summary data. AMIA Annu Symp Proc. 2018 Dec 5;2018:760-769. eCollection 2018. PubMed
Liao P, Dempsey W, Sarker H, Hossain SM, Al'absi M, Klasnja P, Murphy S. Just-in-time but not too much: determining treatment timing in mobile health. Proc ACM Interact Mob Wearable Ubiquitous Technol. 2018 Dec;2(4). pii: 179. doi: 10.1145/3287057. PubMed
Chen L, Pocobelli G, Yu O, Shortreed SM, Osmundson SS, Fuller S, Wartko PD, McCulloch D, Warwick S, Newton KM, Dublin S. Early pregnancy hemoglobin A1C and pregnancy outcomes: a population-based study. Am J Perinatol. 2018 Nov 30. doi: 10.1055/s-0038-1675619. [Epub ahead of print]. PubMed
Mosley JD, Benson MD, Smith JG, Melander O, Ngo D, Shaffer CM, Ferguson JF, Herzig MS, McCarty CA, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Kitchner TE, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Kiryluk K, Mentch FD, Sleiman PM, Karlson EW, Verma SS, Zhu Y, Vasan RS, Yang Q, Denny JC, Roden DM, Gerszten RE, Wang TJ. Probing the virtual proteome to identify novel disease biomarkers. Circulation. 2018;138(22):2469-2481. doi: 10.1161/CIRCULATIONAHA.118.036063. PubMed
James D. Ralston, MD, MPHSenior Investigator |
Jennifer B. McClure, PhDDirector, Investigative Science |
Beverly B. Green, MD, MPHSenior Investigator |
Katharine A. Bradley, MD, MPHSenior Investigator |
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
Yates Coley, PhDAssociate Biostatistics Investigator |
Brian D. Williamson, PhDAssistant Biostatistics Investigator |
Annie Hoopes, MD, MPHActing Assistant Investigator |
Claire Allen, MPHManager, Collaborative Science |
Annie Piccorelli, PhDSenior Collaborative Biostatistician |