Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
Hsu C, Mogk J, Hansell L, Glass JE, Allen C. Rapid Group Analysis Process (Rap-GAP): A novel approach to expedite qualitative health research data analysis. Int J Qual Methods. 2024 May 24. https://doi.org/10.1177/16094069241256275. PubMed
Hazlehurst B, Carrell DS, Bann MA, Nelson J, Gruber S, Slaughter M, Cronkite DJ, Ball R, Floyd JS. Finding uncoded anaphylaxis in electronic health records to estimate the sensitivity of ICD10 codes. Am J Epidemiol. 2024 May 16:kwae063. doi: 10.1093/aje/kwae063. [Epub ahead of print]. PubMed
Carrell DS, Floyd JS, Gruber S, Hazlehurst BL, Heagerty PJ, Nelson JL, Williamson BD, Ball R. A general framework for developing computable clinical phenotype algorithms. J Am Med Inform Assoc. 2024 May 15:ocae121. doi: 10.1093/jamia/ocae121. Online ahead of print. PubMed
Klasnja P, Meza RD, Pullmann MD, Mettert KD, Hawkes R, Palazzo L, Weiner BJ, Lewis CC. Getting cozy with causality: Advances to the causal pathway diagramming method to enhance implementation precision. Implement Res Pract. 2024 Apr 30;5:26334895241248851. doi: 10.1177/26334895241248851. eCollection 2024 Jan-Dec. PubMed
Pocobelli G, Oliver M, Albertson-Junkans L, Gundersen G, Kamineni A. Validation of human immunodeficiency virus diagnosis codes among women enrollees of a U.S. health plan. BMC Health Serv Res. 2024;24(1):234. doi: 10.1186/s12913-024-10685-x. PubMed
James D. Ralston, MD, MPHSenior Investigator |
Jennifer B. McClure, PhDDirector, Investigative Science |
Beverly B. Green, MD, MPHSenior Investigator |
Katharine A. Bradley, MD, MPHSenior Investigator |
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
Yates Coley, PhDAssociate Biostatistics Investigator |
Brian D. Williamson, PhDAssistant Biostatistics Investigator |
Annie Hoopes, MD, MPHActing Assistant Investigator |
Claire Allen, MPHManager, Collaborative Science |
Annie Piccorelli, PhDSenior Collaborative Biostatistician |