Time: 12:00 to 12:55 p.m.
Speaker: Brianna Stubbs, PhD, is the Research Assistant Professor and Director of Translational Science at The Buck Institute for Research on Aging, where her work focuses on researching ketone esters for healthy aging. She completed her PhD in Metabolic Physiology at the University of Oxford. Whilst completing her studies, she was a two-time World Champion in lightweight rowing on Team Great Britain. Brianna spent two years as Research Lead at a San Francisco start-up, where she launched the world's first ketone ester consumer product and received $6M of funding from the U.S. Special Operations Command to investigate exogenous ketone impacts on performance in extreme environments. Since moving to The Buck, she received the inaugural National Institute on Aging Research and Entrepreneurial Development Immersion K01 award, launched a second consumer product, and co-founded a ketone-therapeutic company. In 2023, Dr Stubbs co-established the Buck Clinical Geroscience Unit to run the first onsite clinical studies at The Buck.
Summary: Ketone bodies are endogenous metabolites that primarily function as an energy source during times of low carbohydrate or calorie availability, but are increasingly understood to have signaling functions that intersect with multiple hallmarks of aging. Exogenous "drinkable" ketones offer a tool to increase ketones without dietary changes, and may have applications across health and disease. This talk will give an overview of ketone biology and exogenous ketones, and track their translational path from use in elite athletes and warfighters, to use in clinical studies of frailty.
Join on your computer or mobile app
Click here to join the meeting
Meeting ID: 293 735 733 520 85 Passcode: gB7kS9Tr
Time: 12:00 to 12:55 p.m.
Speaker: Miguel Marino, PhD, is a first-generation Mexican American scientist and professor of biostatistics in the Department of Family Medicine at Oregon Health & Science University (OHSU). He received his undergraduate degree in Mathematics from UCLA and his PhD in biostatistics from Harvard University. He is co-director of the Primary Care Effectiveness and Quality in Latinos Research (PRIMER) Center where he focuses on development and implementation of statistical methodology to address complexities associated with the use of electronic health records (EHRs) to study health equity and changes in health policy among Latinos. Dr. Marino is statistical editor for JAMA Health Forum and was formerly the co-chair of the National Institutes of Health Community Engagement Alliance Needs Assessment & Evaluation Work Group and was on the National Advisory Committee on Racial, Ethnic, and Other Populations for the Census Bureau. In 2022, Dr. Marino was elected as a member to the National Academy of Medicine.
Summary: There have been numerous calls in the medical, public health, and health policy fields for “data disaggregation” (i.e., breaking out data by more granular key characteristics) when studying minority populations, including Latinos, in order to better understand health and health care inequity. The broad racial and ethnic categories whose capture is currently required by the Office of Management and Budget for all federally collected data can mask significant variation within race and ethnicity categories, limiting the ability to target resources where they are needed most.
This presentation will discuss, from a statistician’s point of view, opportunities and challenges for data disaggregation of race and ethnicity data with a case study in Latino populations using electronic health records. The presentation will also explore a current practical question for health systems and researchers: Should primary care clinics routinely collect patient nativity data in electronic health records?
Join on your computer or mobile app
Click here to join the meeting
Meeting ID: 293 735 733 520 85 Passcode: gB7kS9Tr
Time: 12 to 12:55 p.m.
Speaker: Joshua D. Grill, PhD, is the Carla Liggett and Arthur S. Liggett, MD, Endowed Chair, in honor of Frank M. LaFerla at the University of California Irvine (UCI). He is a Professor of Psychiatry and Human Behavior and Neurobiology and Behavior, director of UCI Institute for Memory Impairments and Neurological Disorders (UCI MIND), and co-director of UC Irvine’s Alzheimer’s Disease Research Center, funded by the National Institute on Aging (NIA).
Dr. Grill has published more than 150 scholarly articles and is a regarded leader in Alzheimer’s disease research on clinical trials recruitment and retention, and biomarker disclosure. He holds numerous prominent national leadership positions, including co-leader of the Recruitment Engagement and Retention Unit and the Internal Ethics Committee for the NIA-funded Alzheimer’s Clinical Trial Consortium (ACTC). He is the co-director of the Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD), a program funded by NIA and the Alzheimer’s Association to train the next generation of Alzheimer’s disease and related dementia trialists. He is a member of the Scientific Advisory Board for Maria Shriver’s Women’s Alzheimer’s Movement and for Hilarity for Charity, founded by Seth Rogen and Lauren Miller Rogen.
Summary: This presentation will outline advances in Alzheimer’s disease research and ethical implications to changes in practice.
Land Acknowledgment
Our Seattle offices sit on the occupied land of the Duwamish and by the shared waters of the Coast Salish people, who have been here thousands of years and remain. Learn about practicing land acknowledgment.